Neuro protective effect of barbiturates leading to successful cerebral recovery after drug induced cardiac arrest and following severe multi organ fail
نویسندگان
چکیده
Results 23 year old woman suffered cardiac arrest due to a combined drug overdose with high doses of barbiturates, benzodiazepines and opioids. The patient was found unconscious and after 8 minutes of successful resuscitation transferred to the ICU where she rapidly developed multi organ failure due to the hypoxia and hypo perfusion during the time of cardiac arrest. The organ failure included lever, kidney, lung, pancreas and coagulation, but due to the neuron protective effect of barbiturates, there were no symptoms of cerebral damage. After weeks of stabilizing organ functions the patient was discharged with sustained damage to the kidneys, but no sign of cerebral damage.
منابع مشابه
A Study of Cerebral Performance Categories Based on Initial Rhythm and Resuscitation Time Following In-Hospital Cardiac Arrest in a State Hospital in Turkey
Background: The cerebral performance category (CPC) score is widely used in research and quality assurance to assess neurologic outcome following cardiac arrest. However, little is known about the results of the CPC in Turkey. Objective: This study aimed to determine whether the CPC is associated with the initial rhythm and resuscitation time following re...
متن کاملInitial documented rhythm as a predictor of survivalto-discharge rate after in-hospital cardiac arrest in a tertiary care referral institute, South India: an observational study
Objective: Survival-to-discharge rates following in-hospital cardiac arrest (IHCA) patients remain significantly low. The use of initial documented cardiac rhythm as predictor of Survival-to-discharge is still unclear. This study aimed to assess whether the initial documented rhythm can be used as a predictor of survival-to-discharge following IHCA in an emergency department of the tertiary car...
متن کاملA Case of Cardiac Arrest after Topical Phenylephrine Administration in Adenoidectomy Surgery
Some otolaryngologists administer topical phenylephrine for bleeding control in adenoidectomy surgery. Absorption of this drug from surgical site can lead to increase in blood pressure due to vasoconstriction and then bradycardia related to baroreceptore reflex. Our case was an intraoperative arrest of a 9-yrs-old girl related to administration of topical phenylephrine during adenoidectomy how...
متن کاملProtective effect of silymarin against chemical-induced cardiotoxicity
Cardiac disorders remain one of the most important causes of death in the world. Oxidative stress has been suggested as one of the molecular mechanisms involved in drug-induced cardiac toxicity. Recently, several natural products have been utilized in different studies with the aim to protect the progression of oxidative stress-induced cardiac disorders. There is a large body of evidence that a...
متن کاملProtective effects of combined superoxide dismutase and deferoxamine on recovery of cerebral blood flow and function after cardiac arrest in dogs.
Oxygen free radicals generated during reoxygenation after cardiac arrest may impair recovery of cerebral blood flow and function. In a randomized study in vivo, we tested the following anti-free radical combination therapy administered at the beginning of cardiopulmonary resuscitation after apnea-induced cardiac arrest of 7 minutes: 1) ventilation with 100% nitrogen for 30 seconds to allow the ...
متن کامل